SCHEMBL2428262

SCHEMBL2428262

Cc1ccccc1[S+](c1ccccc1)c1ccccc1.O=C(Cc1ccccc1)OCC(F)(F)S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPK1 P28482 1/20 0.38
PAM P19021 1/20 0.37
KMT2A Q03164 1/20 0.37
ADRB2 P07550 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
MGLL Q99685 2/20 0.33
CES1 P23141 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2425271 0.92 L3MBTL1 (0.44) SMN1; SMN2ALDH1A1L3MBTL1MAPK1KMT2A
SCHEMBL2426324 0.88 SMN1; SMN2 (0.32) SMN1; SMN2CES1
SCHEMBL2424227 0.85 CYP1A2 (0.38) SMN1; SMN2ALDH1A1L3MBTL1MAPK1TSHR
SCHEMBL12292324 0.83 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1L3MBTL1MAPK1PAM
SCHEMBL2428457 0.82 ALDH1A1 (0.51) SMN1; SMN2ALDH1A1L3MBTL1MAPK1PAM
SCHEMBL4353897 0.82 TDP1 (0.37) SMN1; SMN2ALDH1A1L3MBTL1MAPK1KMT2A
SCHEMBL2425912 0.82 KDM4E (0.39) SMN1; SMN2ALDH1A1L3MBTL1MAPK1KMT2A
SCHEMBL4351663 0.79 MEN1 (0.38) SMN1; SMN2ALDH1A1L3MBTL1MAPK1KMT2A
SCHEMBL2424240 0.79 ADRB2 (0.39) SMN1; SMN2ALDH1A1MAPK1KMT2AADRB2
SCHEMBL2425717 0.79 CDC25B (0.41) ALDH1A1L3MBTL1KMT2AADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026390-B2 Photoacid generator containing aromatic ring Korea Kumho Petrochenicals Co., Ltd. (KR) 2011-09-27 US disclosed
US-20100113818-A1 Photoacid generator containing aromatic ring KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113818-A1 Photoacid generator containing aromatic ring HAO2, PAH, PPOX SMN1; SMN2 4843/4885ALDH1A1 1112/4885L3MBTL1 3860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.