SCHEMBL24285353

SCHEMBL24285353

C=C1C=CC(=O)N1CC1CCC(C(=O)NC)CC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
MAPT P10636 1/20 0.37
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
PIM1 P11309 1/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
WRN Q14191 1/20 0.33
HIF1A Q16665 1/20 0.33
WNT3 P56703 1/20 0.32
TP53 P04637 1/20 0.32
NAMPT P43490 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12092098 0.90 LMNA (0.47) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL26712776 0.86 MAPT (0.41) LMNAMAPTKMT2AMEN1SMN1; SMN2
SCHEMBL19749038 0.86 PKM (0.42) LMNAKMT2ATP53
SCHEMBL12377426 0.85 CTH (0.35) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL18294901 0.84 LMNA (0.37) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL18294898 0.84 LMNA (0.37) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL20434503 0.84 EPHX2 (0.40) LMNAKMT2AMEN1SMN1; SMN2HPGD
SCHEMBL14519321 0.83 LMNA (0.38) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL18294905 0.83 ALDH1A1 (0.43) LMNAKMT2AMEN1ALDH1A1CYP1A2
SCHEMBL16483737 0.82 SMN1; SMN2 (0.33) LMNAKMT2AMEN1PIM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339997-A1 CLASS OF PLATINUM COMPOUNDS FOR TREATING CANCER, AND METHOD FOR PREPARATION THEREOF SHANGHAI HAIJU BIOLOGICAL TECHNOLOGY CO., LTD. (CN) 2023-10-26 US disclosed
WO-2022052014-A1 CLASS OF PLATINUM COMPOUNDS FOR TREATING CANCER, AND METHOD FOR PREPARATION THEREOF 上海海聚生物科技有限公司 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339997-A1 CLASS OF PLATINUM COMPOUNDS FOR TREATING CANCER, AND METHOD FOR PREPARATION THEREOF TP53, ERCC4, SLC19A1 LMNA 3986/4885MAPT 4344/4885KMT2A 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.