Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426380 | 0.78 | TRPM8 (0.55) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2179717 | 0.77 | TRPM8 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2427077 | 0.75 | HDAC6 (0.46) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2423902 | 0.75 | LMNA (0.51) | ALDH1A1POLBCSNK2A2CSNK2A1KMT2A | |
| SCHEMBL2420697 | 0.74 | TRPM8 (0.43) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2427248 | 0.74 | GRM6 (0.47) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2423277 | 0.74 | HDAC6 (0.46) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20486119 | 0.74 | NPC1 (0.54) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8840161 | 0.72 | NPC1 (0.51) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27768576 | 0.72 | NPC1 (0.51) | ALDH1A1POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605752-B1 | Sulfonamides for the treatment of congestive heart failure, their compositions and uses. | CYTOKINETICS INC (US) | 2011-09-14 | — | — | EP | disclosed |