Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796236 | 0.84 | NQO2 (0.44) | GAANQO2SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL24287258 | 0.82 | ALDH1A1 (0.50) | NQO2SMN1; SMN2L3MBTL1MAPTTSHR | |
| SCHEMBL26813125 | 0.81 | GAA (0.51) | GAANQO2SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL24287257 | 0.81 | SMN1; SMN2 (0.50) | GAANQO2SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL26817465 | 0.73 | KDM4E (0.59) | GAAMAPTKDM4EHPGDLMNA | |
| SCHEMBL31666386 | 0.73 | HTR1A (0.50) | GAASMN1; SMN2L3MBTL1MAPTHTR1A | |
| SCHEMBL4950654 | 0.73 | HTR1A (0.50) | GAASMN1; SMN2L3MBTL1MAPTHTR1A | |
| SCHEMBL16795314 | 0.72 | ALDH1A1 (0.54) | SMN1; SMN2L3MBTL1MAPTTSHRKDM4E | |
| SCHEMBL18796404 | 0.72 | LCK (0.52) | GAANQO2SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL18796088 | 0.72 | L3MBTL1 (0.47) | GAANQO2SMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076629-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |