Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475954 | 0.90 | HSP90AB1 (0.43) | HSP90AB1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL814001 | 0.88 | HSP90AB1 (0.44) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL1224633 | 0.83 | KDM4E (0.43) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL20563105 | 0.83 | ALDH1A1 (0.38) | HSP90AB1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL1357312 | 0.81 | AURKA (0.37) | ALDH1A1KDRGAAMAPTMEN1 | |
| SCHEMBL20563099 | 0.81 | HSP90AB1 (0.39) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL13527342 | 0.81 | ALDH1A1 (0.48) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL20562211 | 0.81 | ALDH1A1 (0.42) | HSP90AB1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL26685300 | 0.81 | GAA (0.43) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA | |
| SCHEMBL3081523 | 0.78 | KDM4E (0.46) | HSP90AB1ALDH1A1PDGFRBFGFR1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | disclosed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | disclosed |
| EP-3625227-B1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-14 | — | — | EP | disclosed |
| US-11325899-B2 | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-05-10 | — | — | US | disclosed |
| EP-3625222-B1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-21 | — | — | EP | disclosed |
| EP-3625228-B1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-07-07 | — | — | EP | disclosed |
| US-20210115031-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-04-22 | — | — | US | disclosed |
| US-20210113559-A1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-04-22 | — | — | US | disclosed |
| US-20200179383-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2020-06-11 | — | — | US | disclosed |
| EP-3625227-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2020-03-25 | — | — | EP | disclosed |
| CN-101056852-B | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2013-05-01 | — | — | CN | disclosed |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2012-07-12 | — | — | US | disclosed |
| US-8013172-B2 | Cycloalkylphenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-09-06 | — | — | US | disclosed |
| CN-101696197-A | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2010-04-21 | — | — | CN | disclosed |
| CN-101696184-A | iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2010-04-21 | — | — | CN | disclosed |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2009-12-10 | — | — | US | disclosed |
| CN-101056852-A | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-17 | — | — | CN | disclosed |
| US-6746990-B2 | INSECTICIDES, ACARICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | FISCHER REINER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6358887-B1 | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | HSP90AB1 1010/4885ALDH1A1 575/4885PDGFRB 80/4885 |
| US-20200179383-A1 | PHENYL DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER1, PTGER4, PTGER2 | HSP90AB1 933/4885ALDH1A1 527/4885PDGFRB 71/4885 |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | HSP90AB1 1912/4885ALDH1A1 468/4885PDGFRB 62/4885 |
| US-20120178927-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PIKFYVE | HSP90AB1 2595/4885ALDH1A1 4312/4885PDGFRB 3733/4885 |
| US-20210113559-A1 | PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER1, PTGER4, PTGER2 | HSP90AB1 1912/4885ALDH1A1 468/4885PDGFRB 62/4885 |
| US-20210115031-A1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER4, PTGER1, PTGER2 | HSP90AB1 1005/4885ALDH1A1 477/4885PDGFRB 155/4885 |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | CYP19A1, DDT, CYP8B1 | HSP90AB1 1084/4885ALDH1A1 756/4885PDGFRB 4016/4885 |
| US-20090305891-A1 | CYCLOALKYLPHENYL SUBSTITUTED CYCLIC KETOENOLS | PHYKPL, KCNE1, PKM | HSP90AB1 2588/4885ALDH1A1 4442/4885PDGFRB 3637/4885 |
| US-11325899-B2 | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators | PTGER4, PTGER1, PTGER2 | HSP90AB1 1005/4885ALDH1A1 477/4885PDGFRB 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.