SCHEMBL2428846

SCHEMBL2428846

CCc1cc(CC)c2c(c1)-c1ccccc1[PH](=O)O2

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
CSNK2A3 Q8NEV1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430812 0.85 NPC1 (0.38) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL30594715 0.81 GABRA1 (0.34)
SCHEMBL2435459 0.80 PTPN1 (0.38) LMNA
SCHEMBL2435389 0.78 SMN1; SMN2 (0.46) NPC1ALDH1A1LMNAMAPTMAPK1
SCHEMBL30594714 0.75 GPR55 (0.36) NPC1MAPK1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL28376471 0.75 GPR55 (0.36) NPC1MAPK1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL2431409 0.74 ELANE (0.33) ALDH1A1LMNAMAPK1SMN1; SMN2L3MBTL1
SCHEMBL2436972 0.72 NR1H2 (0.37)
SCHEMBL30164963 0.72 FEN1 (0.36) L3MBTL1
SCHEMBL30165037 0.71 MYC (0.33) NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110951048-A Phosphorus-containing curing agent, epoxy resin composition, cured product, prepreg, and laminate 日铁化学材料株式会社 2020-04-03 CN disclosed
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed