SCHEMBL24293873

SCHEMBL24293873

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1ncnc2c1c(Br)cn2[C@@H]1O[C@H](/C=C/CCCO)C2(C)OC(C)(C)OC12C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 13/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27178373 0.82 METTL3 (0.42) METTL3
SCHEMBL20692747 0.70 SRC (0.39) —
SCHEMBL29478326 0.70 ADK (0.34) METTL3
SCHEMBL24293607 0.70 ADK (0.34) METTL3
SCHEMBL30813645 0.69 SSTR4 (0.35) —
SCHEMBL30813372 0.67 LCK (0.35) —
SCHEMBL27217877 0.65 SSTR4 (0.34) —
SCHEMBL29478315 0.64 PRMT5 (0.31) METTL3
SCHEMBL27217986 0.63 LCK (0.35) —
SCHEMBL21221307 0.60 USP30 (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022074391-A1 COMPOUNDS INHIBITORS OF METTL3 STORM THERAPEUTICS LIMITED (GB) 2022-04-14 — — WO disclosed
Send feedback