SCHEMBL2430455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2433501	0.90	ALDH1A1 (0.50)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL2430188	0.83	KDM4E (0.46)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL2434376	0.83	GFER (0.51)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL7531263	0.78	PTGS2 (0.45)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL7262276	0.77	PDE4B (0.51)	MEN1KMT2AALDH1A1MAPTKDM4E
	SCHEMBL7537499	0.76	CASP3 (0.50)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL7261269	0.76	TSPO (0.50)	MEN1KMT2AALDH1A1TP53MAPT
	SCHEMBL7257618	0.76	DYRK1A (0.41)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL1924231	0.75	PTGDR2 (0.44)	MEN1KMT2AALDH1A1TP53CYP3A4
	SCHEMBL7256688	0.75	TNF (0.44)	MEN1KMT2AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.