Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400969 | 0.85 | ESR1 (0.46) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL18200292 | 0.83 | TSHR (0.55) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL29083864 | 0.81 | ESR1 (0.46) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL14613142 | 0.81 | TSHR (0.46) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL10488203 | 0.81 | ALDH1A1 (0.70) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL10728243 | 0.79 | THRB (0.49) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL13291855 | 0.78 | TDP1 (0.56) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL5028692 | 0.78 | ESR1 (0.72) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL26809605 | 0.78 | PHLPP2 (0.50) | ESR1TSHRTDP1ALDH1A1CHRM1 | |
| SCHEMBL14613091 | 0.78 | TDP1 (0.52) | ESR1TSHRTDP1ALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119567-A1 | NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |