Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.65 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12346768 | 0.82 | NCF1 (0.67) | NCF1CXCR4HRH3ACHEBACE1 | |
| SCHEMBL21820699 | 0.81 | ALDH1A1 (0.64) | CXCR4HRH3ACHEBACE1BCHE | |
| SCHEMBL21604394 | 0.81 | ALDH1A1 (0.62) | HRH3ACHEBACE1CCR3MEN1 | |
| Hydrochloric Acid SCHEMBL1934432 | 0.81 | NCF1 (0.65) | NCF1CXCR4HRH3ACHEBACE1 | |
| SCHEMBL24321062 | 0.80 | CCR2 (0.51) | ACHEMEN1KMT2A | |
| SCHEMBL25856039 | 0.80 | HRH3 (0.50) | CXCR4HRH3ACHECCR3MEN1 | |
| SCHEMBL3156587 | 0.80 | LMNA (0.59) | HRH3ACHECCR3ALDH1A1 | |
| SCHEMBL2735346 | 0.80 | CCR3 (0.71) | CXCR4ACHECCR3L3MBTL1ALDH1A1 | |
| SCHEMBL2237928 | 0.79 | NCF1 (0.63) | NCF1CXCR4HRH3ACHEBACE1 | |
| SCHEMBL18419740 | 0.79 | HRH3 (0.53) | HRH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078470-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |