Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21820699 | 0.84 | ALDH1A1 (0.64) | HRH3ALDH1A1MEN1KMT2ACXCR4 | |
| SCHEMBL21604394 | 0.84 | ALDH1A1 (0.62) | HRH3CCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL3156587 | 0.83 | LMNA (0.59) | HRH3CCR3ALDH1A1ACHE | |
| SCHEMBL2735346 | 0.82 | CCR3 (0.71) | CCR3ALDH1A1CXCR4ACHE | |
| SCHEMBL15096667 | 0.82 | HRH3 (0.46) | HRH3CCR3ALDH1A1MEN1CYP2D6 | |
| SCHEMBL14032717 | 0.81 | KDM1A (0.56) | CCR3ACHEMAOB | |
| SCHEMBL24307299 | 0.80 | NCF1 (0.65) | HRH3CCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL20843171 | 0.80 | SMN1; SMN2 (0.56) | HRH3ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL25884309 | 0.80 | ALDH1A1 (0.51) | HRH3CCR3ALDH1A1MEN1KMT2A | |
| SCHEMBL25531006 | 0.80 | TEAD1 (0.52) | HRH3CCR3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |