Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310447 | 0.89 | USP1 (0.33) | GPR39 | |
| SCHEMBL26806627 | 0.82 | CHEK1 (0.36) | — | |
| SCHEMBL24309696 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL24309257 | 0.77 | USP1 (0.33) | — | |
| SCHEMBL24310509 | 0.77 | CDK2 (0.32) | — | |
| SCHEMBL24309507 | 0.76 | CYP1A2 (0.35) | F10GPR39 | |
| SCHEMBL24298137 | 0.74 | GPR39 (0.35) | F10GPR39 | |
| SCHEMBL24310766 | 0.74 | GPR39 (0.44) | GPR39 | |
| SCHEMBL24310084 | 0.74 | LMNA (0.36) | — | |
| SCHEMBL24310109 | 0.73 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |