Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309479 | 0.91 | HTR1A (0.33) | BRPF1BRD9BRD4 | |
| SCHEMBL24310359 | 0.90 | BRD9 (0.34) | BRPF1BRD9BRD4 | |
| SCHEMBL24310478 | 0.87 | BRD4 (0.32) | BRPF1BRD9BRD4 | |
| SCHEMBL29566934 | 0.85 | HTR7 (0.39) | BRPF1BRD9BRD4TNK2 | |
| SCHEMBL24310020 | 0.85 | HTR7 (0.39) | BRPF1BRD9BRD4TNK2 | |
| SCHEMBL24309536 | 0.83 | BRPF1 (0.34) | BRPF1BRD9BRD4TNK2 | |
| SCHEMBL24310049 | 0.83 | PAK1 (0.36) | BRPF1BRD9BRD4TNK2 | |
| SCHEMBL24310089 | 0.82 | DRD2 (0.35) | BRPF1BRD9BRD4 | |
| SCHEMBL24310513 | 0.82 | MEN1 (0.33) | BRPF1BRD9BRD4 | |
| SCHEMBL24310360 | 0.81 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |