Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313337 | 0.83 | CYP1A1 (0.37) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL24313344 | 0.82 | PRKDC (0.37) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL21855911 | 0.79 | TDP1 (0.43) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL28360529 | 0.79 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL24068855 | 0.77 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL14656252 | 0.77 | SOS1 (0.44) | ALDH1A1L3MBTL1NFE2L2LMNAKMT2A | |
| SCHEMBL96291 | 0.76 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL14667727 | 0.76 | HTR2A (0.39) | ALDH1A1L3MBTL1KDM4ENFE2L2KMT2A | |
| SCHEMBL14667733 | 0.75 | KDM4E (0.47) | ALDH1A1L3MBTL1KDM4ETDP1NFE2L2 | |
| SCHEMBL8544716 | 0.75 | MAOA (0.41) | ALDH1A1L3MBTL1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | PKD2, PKD1, MUC1 | ALDH1A1 3071/4885L3MBTL1 1692/4885CYP1A2 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.