Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656252 | 0.86 | SOS1 (0.44) | ALDH1A1L3MBTL1POLBCASP6CYP2A6 | |
| SCHEMBL24313344 | 0.86 | PRKDC (0.37) | CYP1A1CYP1A2CYP1B1ALDH1A1TRIM24 | |
| SCHEMBL21855911 | 0.86 | TDP1 (0.43) | CYP1A1CYP1A2CYP1B1ALDH1A1TRIM24 | |
| SCHEMBL30509805 | 0.85 | ERN1 (0.42) | CYP1A1CYP1A2CYP1B1ALDH1A1TRIM24 | |
| SCHEMBL24312922 | 0.83 | ALDH1A1 (0.59) | CYP1A1CYP1A2CYP1B1ALDH1A1TRIM24 | |
| SCHEMBL14656089 | 0.82 | ALDH1A1 (0.39) | CYP1A2ALDH1A1L3MBTL1POLBCASP6 | |
| SCHEMBL8544716 | 0.81 | MAOA (0.41) | ALDH1A1L3MBTL1POLBSMN1; SMN2DRD1 | |
| SCHEMBL14667726 | 0.81 | ALDH1A1 (0.50) | CYP1A2ALDH1A1L3MBTL1POLBCASP6 | |
| SCHEMBL14656299 | 0.80 | KIF11 (0.53) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL14667727 | 0.79 | HTR2A (0.39) | ALDH1A1L3MBTL1POLBCASP6CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096441-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | PKD2, PKD1, MUC1 | CYP1A1 4001/4885CYP1A2 3681/4885CYP1B1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.