Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.48 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 12/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611067 | 1.00 | ADK (0.48) | ADKHASPINMETTL3PRMT5DOT1L | |
| SCHEMBL29478319 | 0.86 | ADK (0.47) | ADKMETTL3PRMT5 | |
| SCHEMBL29478322 | 0.84 | ADK (0.54) | ADKMETTL3PRMT5DOT1L | |
| SCHEMBL29478317 | 0.84 | ADK (0.47) | ADKMETTL3PRMT5 | |
| SCHEMBL24487770 | 0.82 | AHCY (0.59) | — | |
| SCHEMBL29478310 | 0.82 | ADK (0.51) | ADKMETTL3PRMT5DOT1LPRMT3 | |
| SCHEMBL24313507 | 0.79 | METTL3 (0.46) | ADKHASPINMETTL3PRMT5DOT1L | |
| SCHEMBL29611126 | 0.79 | METTL3 (0.46) | ADKHASPINMETTL3PRMT5DOT1L | |
| SCHEMBL24313825 | 0.78 | METTL3 (0.60) | METTL3PRMT5 | |
| SCHEMBL29610866 | 0.78 | METTL3 (0.60) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |