Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 7/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313803 | 0.81 | KDM4E (0.44) | LIPEDGAT1SCN9ASCN10AHIF1A | |
| SCHEMBL24313800 | 0.80 | LMNA (0.46) | LMNAPDE4BSCN9AHPGDSMAPK1 | |
| SCHEMBL24313817 | 0.79 | LMNA (0.46) | LMNAPDE4BSCN9AHPGDSMAPK1 | |
| SCHEMBL23474121 | 0.78 | DGAT1 (0.43) | LIPEDGAT1LMNAMAPK1 | |
| SCHEMBL4561669 | 0.77 | SNCA (0.47) | DGAT1HPGDSALPL | |
| SCHEMBL3451006 | 0.77 | ALOX15 (0.44) | DGAT1HPGDSMAPK1HIF1AALPL | |
| SCHEMBL1623079 | 0.76 | PTPN11 (0.47) | DGAT1PDE4BHIF1A | |
| SCHEMBL29750908 | 0.76 | PTPN11 (0.47) | DGAT1PDE4BHIF1A | |
| SCHEMBL31162850 | 0.72 | HDAC1 (0.44) | DGAT1LMNAHIF1A | |
| SCHEMBL15774244 | 0.72 | HDAC1 (0.44) | DGAT1LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022077161-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |