Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 4/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24313798 | 0.81 | LIPE (0.43) | DGAT1LIPESCN9ASCN10AALPL | |
| SCHEMBL4561669 | 0.77 | SNCA (0.47) | ALDH1A1DGAT1LPLLIPGALPL | |
| SCHEMBL27080362 | 0.76 | ALPL (0.41) | KDM4EALDH1A1POLBDGAT1LPL | |
| SCHEMBL29984560 | 0.76 | ALPL (0.41) | KDM4EALDH1A1POLBDGAT1LPL | |
| SCHEMBL20539098 | 0.73 | LPL (0.49) | LPLLIPGP4HB | |
| SCHEMBL14842080 | 0.70 | CYP1A2 (0.45) | LPLLIPGALPLHIF1ASNCA | |
| SCHEMBL6033638 | 0.69 | LPL (0.47) | LPLLIPGALPLSNCA | |
| SCHEMBL14721612 | 0.69 | EGFR (0.43) | LPLLIPGALPLSNCA | |
| SCHEMBL7601195 | 0.68 | LIPG (0.58) | DGAT1LPLLIPGSNCA | |
| SCHEMBL2220666 | 0.68 | SNCA (0.40) | ALDH1A1DGAT1LPLLIPGALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022077161-A1 | COMPOUNDS FOR MODULATING ACTIVITY OF FXR AND USES THEREOF | GANNEX PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |