Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 11/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620820 | 0.86 | TRPV3 (0.45) | TRPV3TAS1R3TAS1R1TAS1R2SSTR3 | |
| SCHEMBL27010653 | 0.82 | TRPV3 (0.39) | TRPV3SSTR3PIM1KCNH2KDM1A | |
| SCHEMBL27010638 | 0.77 | MAOA (0.52) | KDM1AMAOAMAOB | |
| SCHEMBL27010659 | 0.72 | KDM1A (0.47) | SSTR3KDM1AMAOAMAOB | |
| SCHEMBL26641275 | 0.70 | TRPV3 (0.42) | TRPV3KDM1AMAOAMAOB | |
| SCHEMBL24316213 | 0.70 | TSHR (0.43) | TAS1R3TAS1R1SSTR3 | |
| SCHEMBL24316207 | 0.68 | TRPV3 (0.41) | TRPV3SSTR3KCNH2KDM1AMAOA | |
| SCHEMBL20063373 | 0.68 | KDM1A (0.47) | SSTR3KDM1AMAOAGRIN2B | |
| SCHEMBL27010643 | 0.68 | KDM1A (0.47) | SSTR3KDM1AMAOAGRIN2B | |
| SCHEMBL24316209 | 0.68 | KDM1A (0.52) | SSTR3KCNH2KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081925-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |