Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PRKACA | P17612 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325636 | 0.94 | MEN1 (0.39) | MAPK1PRNPTSHRPPARGHTT | |
| SCHEMBL2428388 | 0.82 | MAPK1 (0.40) | MAPK1HTTRAB9AMEN1KMT2A | |
| SCHEMBL2430453 | 0.82 | GPR35 (0.43) | RXFP1GPR35RAB9AMEN1KMT2A | |
| SCHEMBL28322304 | 0.74 | QDPR (0.45) | MAPK1PRNPTSHRPPARGHTT | |
| SCHEMBL958906 | 0.72 | LIMK1 (0.54) | MAPK1LIMK1IKBKBRAB9AMEN1 | |
| SCHEMBL20695473 | 0.72 | MGLL (0.36) | — | |
| SCHEMBL2429181 | 0.71 | NOTUM (0.30) | — | |
| SCHEMBL21714170 | 0.70 | LIMK1 (0.51) | LIMK1IKBKBRAB9AMEN1KMT2A | |
| SCHEMBL693361 | 0.70 | BCKDK (0.60) | TSHRRXFP1GPR35RAB9ANPC1 | |
| SCHEMBL912683 | 0.69 | RAB9A (0.52) | TSHRRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |