Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26717311 | 0.76 | NOS3 (0.42) | NOS3NOS1NOS2MAPTTP53 | |
| SCHEMBL16440327 | 0.76 | MAPK8 (0.42) | NOS3NOS1NOS2MAPTMAPK1 | |
| SCHEMBL17876771 | 0.73 | TSHR (0.43) | MAPTHTTKDM4ETSHR | |
| SCHEMBL19208377 | 0.72 | MAPK8 (0.48) | MAPTTSHR | |
| SCHEMBL16433339 | 0.68 | RAB9A (0.42) | MAPTKDM4ECYP2A6KDM4CRAB9A | |
| SCHEMBL19208697 | 0.66 | MAPT (0.48) | MAPTKDM4E | |
| SCHEMBL18982536 | 0.65 | CTSK (0.41) | KDM4C | |
| SCHEMBL19236792 | 0.65 | MAPT (0.47) | MAPTTP53MAPK1L3MBTL1KDM4E | |
| SCHEMBL23110370 | 0.62 | HTT (0.50) | MAPTHTTATML3MBTL1KDM4E | |
| SCHEMBL20161329 | 0.60 | ENPP2 (0.39) | HTTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | EUROCHEM ANTWERPEN (BE) | 2023-11-09 | — | — | US | disclosed |
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | EUROCHEM ANTWERPEN (BE) | 2023-11-09 | — | — | US | disclosed |
| WO-2022053661-A2 | PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | EUROCHEM ANTWERPEN (BE) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357099-A1 | PYRAZOLO [3,4-B] PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR | CBR1, CYC1, CBR3 | NOS3 8/4885NOS1 6/4885NOS2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.