Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17876771 | 0.81 | TSHR (0.43) | MAPTTDP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19208377 | 0.80 | MAPK8 (0.48) | MAPK8MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16433339 | 0.80 | RAB9A (0.42) | MAPK8RAB9AMAPTCYP2A6KDM4E | |
| SCHEMBL24182151 | 0.78 | ADORA2A (0.62) | MAPK8MAPTTDP1CYP1A2CYP3A4 | |
| SCHEMBL24316737 | 0.76 | NOS3 (0.44) | RAB9AMAPTL3MBTL1CYP2A6KDM4E | |
| SCHEMBL19208697 | 0.76 | MAPT (0.48) | MAPK8MAPTKDM4EALDH1A1 | |
| SCHEMBL19236792 | 0.74 | MAPT (0.47) | MAPK8MAPTTDP1L3MBTL1KDM4E | |
| SCHEMBL9043059 | 0.72 | MAPK8 (0.53) | MAPK8MAPTPTGER4KDM4EALDH1A1 | |
| SCHEMBL10095354 | 0.71 | SMN1; SMN2 (0.50) | RAB9ATDP1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL11152305 | 0.71 | ADORA2A (0.38) | MAPK8RAB9AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027605-B1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-11-08 | — | — | EP | disclosed |
| US-9737510-B2 | Indazole compounds and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-22 | — | — | US | disclosed |
| US-9737510-B2 | Indazole compounds and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-08-22 | — | — | US | disclosed |
| US-20160185759-A1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-30 | — | — | US | disclosed |
| US-20160185759-A1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-30 | — | — | US | disclosed |
| WO-2015015519-A1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185759-A1 | NOVEL INDAZOLE COMPOUNDS AND A PROCESS FOR THE PREPARATION THEREOF | GPR119, INSR, CYP11B1 | MAPK8 1262/4885RAB9A 859/4885MAPT 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.