Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.40 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988039 | 0.85 | HTR1A (0.46) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL367520 | 0.68 | TDP1 (0.52) | FFAR4ALDH1A1 | |
| SCHEMBL20175295 | 0.68 | HTR1A (0.43) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL20179434 | 0.68 | HTR1A (0.43) | HTR1ADRD2LMNAFFAR4ALDH1A1 | |
| SCHEMBL30628475 | 0.67 | HTR1A (0.67) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL29099302 | 0.67 | HTR1A (0.67) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL16294248 | 0.67 | USP28 (0.69) | PTGER1USP28USP25LMNAHTT | |
| SCHEMBL18894534 | 0.67 | HTR1A (0.53) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL20006769 | 0.67 | HTR1A (0.49) | HTR1ADRD2LMNAFFAR4ALDH1A1 | |
| SCHEMBL18417242 | 0.67 | ALDH1A1 (0.45) | HTR1ADRD2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |