Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317465 | 0.90 | OPRD1 (0.48) | OPRD1RAB9A | |
| SCHEMBL26619441 | 0.86 | OPRD1 (0.51) | OPRD1MEN1KMT2ARAB9AHTR1D | |
| SCHEMBL24317470 | 0.85 | ADRA2A (0.44) | OPRD1MEN1KMT2AMAOB | |
| SCHEMBL24315724 | 0.82 | OPRD1 (0.48) | OPRD1MEN1KMT2ARAB9A | |
| SCHEMBL1719051 | 0.75 | ALDH1A1 (0.48) | — | |
| SCHEMBL26619435 | 0.75 | SIGMAR1 (0.50) | OPRD1RAB9AHTR1DHTR1B | |
| SCHEMBL12126130 | 0.74 | OPRM1 (0.56) | OPRD1MEN1KMT2A | |
| SCHEMBL12126132 | 0.73 | OPRM1 (0.54) | OPRD1 | |
| SCHEMBL13061105 | 0.72 | SIGMAR1 (0.43) | OPRD1MEN1KMT2ARAB9AHTR1D | |
| SCHEMBL13061092 | 0.72 | SIGMAR1 (0.43) | OPRD1MEN1KMT2ARAB9AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |