Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24319629 | 0.80 | ADRA1B (0.31) | — | |
| SCHEMBL5645558 | 0.79 | NOS3 (0.33) | TDP1TMEM97SIGMAR1 | |
| SCHEMBL25565965 | 0.79 | NOS3 (0.36) | TDP1 | |
| SCHEMBL24319184 | 0.78 | NCF1 (0.37) | TMEM97SIGMAR1 | |
| SCHEMBL23129125 | 0.78 | NCF1 (0.37) | TMEM97SIGMAR1 | |
| SCHEMBL27391655 | 0.77 | NOS3 (0.35) | TMEM97SIGMAR1 | |
| SCHEMBL27269119 | 0.76 | EPHX1 (0.31) | — | |
| SCHEMBL3473819 | 0.75 | SLC6A2 (0.37) | TMEM97SIGMAR1 | |
| SCHEMBL5651239 | 0.74 | ADRA1B (0.39) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3474532 | 0.74 | SLC6A2 (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |