SCHEMBL2432236

SCHEMBL2432236

CCCCC=C[SiH](C)O[SiH3].C[SiH](C)O[SiH3]

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 2/20 0.30
LPAR3 Q9UBY5 2/20 0.30
TSHR P16473 2/20 0.30
PPARA Q07869 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LPAR1 Q92633 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613353 0.96 TSHR (0.32) LPAR2LPAR3TSHRPPARAALDH1A1
SCHEMBL8853337 0.88 FAAH (0.42) PPARA
SCHEMBL17889186 0.73 LPAR2 (0.34) LPAR2LPAR3TSHRALDH1A1LPAR1
SCHEMBL7457898 0.73 PTPN1 (0.46) PPARA
SCHEMBL27777818 0.72 TSHR (0.34) LPAR2LPAR3TSHRALDH1A1LPAR1
SCHEMBL9252237 0.72 TSHR (0.34) LPAR2LPAR3TSHRALDH1A1LPAR1
SCHEMBL8992206 0.71 TSHR (0.39) LPAR2LPAR3TSHRPPARAALDH1A1
SCHEMBL216757 0.71
SCHEMBL5968580 0.71
SCHEMBL2058705 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2363438-A1 Optically clear biofouling resistant coating compositions for marine instruments and application methods Severn Marine Technologies, LLC (US) 2011-09-07 EP disclosed
WO-2008084747-A2 SOLVENTLESS CURED RELEASE COATING-FORMING ORGANOPOLYSILOXANE COMPOSITION AND SHEET-FORM SUBSTRATE HAVING CURED RELEASE COATING DOW CORNING TORAY CO., LTD. (JP) 2008-07-17 WO disclosed
EP-0371405-A2 Organopolysiloxane composition for the formation of a release film Dow Corning Toray Silicone Company Ltd. (JP) 1990-06-06 EP disclosed