Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777818 | 1.00 | TSHR (0.34) | TSHRFAAHTRPV1ALDH1A1LPAR2 | |
| SCHEMBL613353 | 0.75 | TSHR (0.32) | TSHRFAAHTRPV1ALDH1A1LPAR2 | |
| SCHEMBL2432236 | 0.72 | LPAR2 (0.30) | TSHRALDH1A1LPAR2LPAR3LPAR1 | |
| SCHEMBL8992206 | 0.71 | TSHR (0.39) | TSHRFAAHTRPV1ALDH1A1LPAR2 | |
| SCHEMBL216757 | 0.71 | — | — | |
| SCHEMBL5968580 | 0.71 | — | — | |
| SCHEMBL2058705 | 0.71 | — | — | |
| Water SCHEMBL27852585 | 0.69 | TSHR (0.38) | TSHRFAAHTRPV1ALDH1A1LPAR2 | |
| SCHEMBL8853337 | 0.68 | FAAH (0.42) | FAAHTRPV1 | |
| SCHEMBL9252240 | 0.68 | LPAR2 (0.30) | TSHRALDH1A1LPAR2LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432761-B1 | Method to reduce compression set in silanol-containing silicone elastomer bases | DOW CORNING (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5081172-A | Gaskets, seals | DOW CORNING CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0432761-A2 | Method to reduce compression set in silanol-containing silicone elastomer bases | DOW CORNING CORPORATION (US) | 1991-06-19 | — | — | EP | disclosed |