SCHEMBL24322644

SCHEMBL24322644

N#Cc1nccc(-c2ccccc2)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LRRK2 Q5S007 5/20 0.45
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
CRHBP P24387 1/20 0.42
RAB9A P51151 1/20 0.42
CRHR2 Q13324 1/20 0.42
KDM4E B2RXH2 3/20 0.41
LMNA P02545 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
NUDT1 P36639 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
ERBB2 P04626 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5481613 0.80 ALDH1A1 (0.49) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL27544440 0.80 ALDH1A1 (0.61) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL1008743 0.76 ALOX15 (0.44) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL16681058 0.75 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL7861011 0.75 LRRK2 (0.43) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL1350031 0.73 NPSR1 (0.43) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL28083706 0.73 CCNA2 (0.44) ALDH1A1L3MBTL1LRRK2KDM4ELMNA
SCHEMBL1007112 0.72 ALDH1A1 (0.42) ALDH1A1LRRK2MAPTRAB9AKDM4E
SCHEMBL30692909 0.72 ALDH1A1 (0.42) ALDH1A1LRRK2MAPTRAB9AKDM4E
SCHEMBL3301267 0.72 BACE1 (0.41) ALDH1A1MEN1KMT2ACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163441-B Organic compound, organic light emitting diode comprising the same, and organic light emitting device 乐金显示有限公司 2024-07-23 CN disclosed
CN-114163441-A Organic compound, organic light emitting diode including the same, and organic light emitting device 乐金显示有限公司 2022-03-11 CN disclosed
US-20220077402-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC COMPOUND LG DISPLAY CO., LTD. (KR) 2022-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220077402-A1 ORGANIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE ORGANIC COMPOUND OCIAD1, OCIAD2, NLRP3 ALDH1A1 1200/4885MEN1 3800/4885KMT2A 2196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.