Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544440 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL24322462 | 0.81 | CNR2 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL24322644 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL1940527 | 0.78 | LRRK2 (0.56) | ALDH1A1L3MBTL1LRRK2KDM4ELMNA | |
| SCHEMBL1008743 | 0.77 | ALOX15 (0.44) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL996432 | 0.72 | CCNA2 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL2489243 | 0.72 | LRRK2 (0.43) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL30143359 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| Phosphine SCHEMBL8460251 | 0.72 | CHEK1 (0.40) | ALDH1A1MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL10427642 | 0.71 | ERBB2 (0.53) | ALDH1A1CYP1A2LRRK2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128658-A1 | FLUORESCENT DYES, METHODS AND USES THEREOF | DHX15, DHX35, DUT | ALDH1A1 2503/4885MEN1 3602/4885KMT2A 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.