Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24324680 | 0.87 | NPC1 (0.35) | NPC1RAB9APKMSMN1; SMN2HTT | |
| SCHEMBL22992111 | 0.79 | TRPV1 (0.38) | POLBGRM5 | |
| SCHEMBL24324949 | 0.78 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22992106 | 0.78 | FAAH (0.38) | HTTALDH1A1KDM4EGRM5KMT2A | |
| SCHEMBL23344423 | 0.76 | CNR1 (0.32) | HTTPOLB | |
| SCHEMBL22992172 | 0.76 | PDE4B (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL29342691 | 0.74 | DPP4 (0.39) | — | |
| SCHEMBL22907832 | 0.74 | ACACB (0.32) | POLB | |
| SCHEMBL22992066 | 0.74 | GRM4 (0.39) | NPC1RAB9ASMN1; SMN2KDM4EGAA | |
| SCHEMBL22942017 | 0.74 | NPC1 (0.41) | NPC1RAB9APKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | DDT, DHFR, CCNB3 | NPC1 4792/4885RAB9A 2861/4885PKM 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.