Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942012 | 0.87 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL22992106 | 0.86 | FAAH (0.38) | ALDH1A1TSHRGRM5 | |
| SCHEMBL24324680 | 0.84 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL22941569 | 0.82 | — | — | |
| SCHEMBL22941982 | 0.81 | SMYD3 (0.43) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL22941978 | 0.81 | JAK2 (0.34) | — | |
| SCHEMBL22941557 | 0.79 | EGFR (0.39) | NPC1RAB9ASMN1; SMN2PKMLMNA | |
| SCHEMBL22941522 | 0.77 | DRD2 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21344636 | 0.77 | L3MBTL1 (0.44) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL22941572 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018834-A1 | CYCLIC DIONES AS HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-02-04 | — | — | WO | disclosed |