Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 4/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992106 | 0.91 | FAAH (0.38) | ALDH1A1HTTKDM4EBTKGRM5 | |
| SCHEMBL24324679 | 0.87 | NPC1 (0.37) | NPC1RAB9APKMALDH1A1HTT | |
| SCHEMBL22942017 | 0.84 | NPC1 (0.41) | NPC1RAB9APKMALDH1A1SMN1; SMN2 | |
| SCHEMBL21344636 | 0.83 | L3MBTL1 (0.44) | ALDH1A1SMN1; SMN2GAACYP3A4CYP2D6 | |
| SCHEMBL22345626 | 0.83 | FASN (0.31) | — | |
| SCHEMBL22942059 | 0.81 | RAB9A (0.35) | NPC1RAB9APKMALDH1A1KDM4E | |
| SCHEMBL22992194 | 0.81 | TRPV1 (0.36) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL22992236 | 0.81 | NAMPT (0.38) | ALDH1A1KDM4ESMN1; SMN2CYP2D6TSHR | |
| SCHEMBL24325236 | 0.81 | — | — | |
| SCHEMBL24325242 | 0.81 | GRM5 (0.32) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | DDT, DHFR, CCNB3 | NPC1 4792/4885RAB9A 2861/4885PKM 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.