SCHEMBL24326752

SCHEMBL24326752

O=C(O)c1nccc2cc(Br)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.50
KDM4E B2RXH2 4/20 0.49
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
RXFP1 Q9HBX9 2/20 0.44
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
PIM1 P11309 1/20 0.40
APAF1 O14727 1/20 0.40
TDP2 O95551 1/20 0.40
NSD2 O96028 1/20 0.40
CASP3 P42574 1/20 0.40
PPP1CA P62136 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
UBA2 Q9UBT2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29571020 1.00 PLAU (0.50) PLAUKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL28784070 0.88 PLAU (0.51) PLAUKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL19794695 0.85 PLAU (0.49) PLAUKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL29571062 0.81 PLAU (0.46) PLAURXFP1APAF1TDP2NSD2
SCHEMBL24325939 0.81 PLAU (0.46) PLAURXFP1APAF1TDP2NSD2
SCHEMBL274802 0.81 IGFBP3 (0.43) PLAUKDM4EALDH1A1MEN1KMT2A
SCHEMBL4726584 0.80 IGFBP3 (0.47) PLAUKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL755959 0.79 KDM4E (0.47) KDM4EALDH1A1KMT2AASPHKDM8
SCHEMBL754061 0.79 KMO (0.42) KDM4EALDH1A1SMN1; SMN2RXFP1ASPH
SCHEMBL2002683 0.77 ALDH1A1 (0.49) PLAUALDH1A1SMN1; SMN2RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459934-B2 Pesticidal compounds BASF SE (DE) 2025-11-04 US disclosed
EP-4598923-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS The Regents of the University of California (US) 2025-08-13 EP disclosed
CN-113166063-B Pesticidal compounds 巴斯夫欧洲公司 2025-02-25 CN disclosed
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240201205-A1 METHOD FOR DETECTING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO disclosed
US-20240018161-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2024-01-18 US disclosed
CN-116670143-A Modulators of cystic fibrosis transmembrane conductance regulator 弗特克斯药品有限公司 2023-08-29 CN disclosed
EP-4225447-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2023-08-16 EP disclosed
WO-2022076625-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-04-14 WO disclosed
WO-2022076625-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-04-14 WO disclosed
US-20220002284-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2022-01-06 US disclosed
EP-3887357-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2021-10-06 EP disclosed
CN-113166063-A Pesticidal compounds 巴斯夫欧洲公司 2021-07-23 CN disclosed
CN-108203433-B ROCK inhibitor and application thereof 成都先导药物开发股份有限公司 2020-07-03 CN disclosed
WO-2020109039-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2020-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS MAPT, HTT, PSEN1 PLAU 450/4885KDM4E 4298/4885ALDH1A1 4342/4885
US-20240018161-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B PLAU 4013/4885KDM4E 4201/4885ALDH1A1 4077/4885
US-12459934-B2 Pesticidal compounds NIT2, PNMT, THOP1 PLAU 4022/4885KDM4E 3621/4885ALDH1A1 1528/4885
US-20220002284-A1 PESTICIDAL COMPOUNDS NIT2, PNMT, THOP1 PLAU 4022/4885KDM4E 3621/4885ALDH1A1 1528/4885
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS PRNP, PSEN1, SNCA PLAU 546/4885KDM4E 4814/4885ALDH1A1 4385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.