Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.30 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545277 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNAALOX15BLMPMP22 | |
| SCHEMBL17274505 | 0.78 | GABRP (0.46) | LMNABLMPMP22GABRPGABRD | |
| SCHEMBL5798252 | 0.78 | LCK (0.50) | ALDH1A1LMNASLC15A2PAOXTRPA1 | |
| SCHEMBL971093 | 0.75 | — | — | |
| SCHEMBL28409342 | 0.74 | — | — | |
| SCHEMBL28465687 | 0.74 | LCK (0.44) | ALDH1A1CA1CA2LCKPPARD | |
| SCHEMBL3870432 | 0.73 | KMT2A (0.44) | ALDH1A1LMNASLC15A2PAOXALOX15 | |
| SCHEMBL21026616 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNASLC15A2PAOXALOX15 | |
| SCHEMBL20107051 | 0.73 | KMT2A (0.44) | ALDH1A1LMNASLC15A2PAOXALOX15 | |
| SCHEMBL26139447 | 0.73 | ZDHHC7 (0.55) | ALDH1A1LMNASLC15A2TRPA1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |