Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | UBE2M | P61081 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327550 | 0.93 | DCUN1D1 (0.60) | TP53LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24327446 | 0.89 | MTOR (0.48) | LMNAMAPTMTORKIF11 | |
| SCHEMBL24328772 | 0.87 | MTOR (0.58) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24327551 | 0.84 | MTOR (0.68) | TP53MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL24327424 | 0.83 | MTOR (0.48) | TP53LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24327548 | 0.82 | MTOR (0.53) | LMNAALDH1A1DCUN1D1UBE2MNPSR1 | |
| SCHEMBL11145412 | 0.77 | ALDH1A1 (0.66) | TP53LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL24327966 | 0.75 | UBE2M (0.52) | ALDH1A1DCUN1D1MAPTHTTUBE2M | |
| Fluometuron SCHEMBL4658882 | 0.75 | TP53 (0.91) | TP53LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24327968 | 0.74 | ALDH1A1 (0.65) | TP53MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |