Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.58 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327551 | 0.93 | MTOR (0.68) | MTORKIF11EPHX2ALDH1A1PTGS1 | |
| SCHEMBL24327446 | 0.91 | MTOR (0.48) | MTORKIF11CA12CA1CA2 | |
| SCHEMBL24327424 | 0.87 | MTOR (0.48) | MTORKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL24327422 | 0.87 | TP53 (0.56) | MTORKIF11ALDH1A1RAB9AMEN1 | |
| SCHEMBL24327548 | 0.81 | MTOR (0.53) | MTORALDH1A1LMNA | |
| SCHEMBL24327550 | 0.79 | DCUN1D1 (0.60) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL24327968 | 0.77 | ALDH1A1 (0.65) | MTOREPHX2ALDH1A1NPC1RAB9A | |
| SCHEMBL24327547 | 0.77 | ALDH1A1 (0.53) | MTORALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL24327967 | 0.77 | FPR2 (0.52) | MTOREPHX2ALDH1A1KMT2AMAPT | |
| SCHEMBL29140947 | 0.75 | MTOR (0.75) | MTOREPHX2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |