Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 3/20 | 0.45 |
| ▸ | RGS8 | P57771 | 3/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327921 | 0.95 | TRPV1 (0.48) | RGS4RGS8TRPV1P2RX3CHRM5 | |
| SCHEMBL24327425 | 0.93 | P2RX3 (0.47) | RGS4RGS8TRPV1P2RX3CHRM5 | |
| SCHEMBL24327510 | 0.88 | RGS4 (0.52) | RGS4RGS8P2RX3CHRM5MEN1 | |
| SCHEMBL24328735 | 0.86 | P2RX3 (0.44) | RGS4RGS8TRPV1P2RX3CHRM5 | |
| SCHEMBL24327923 | 0.86 | RGS4 (0.60) | RGS4RGS8MEN1KMT2ACTSK | |
| SCHEMBL24327924 | 0.85 | PGR (0.49) | RGS4RGS8KMT2ACYP3A4DAO | |
| SCHEMBL24328815 | 0.85 | RGS4 (0.50) | RGS4RGS8CFTRMEN1POLB | |
| SCHEMBL24327511 | 0.85 | RGS4 (0.46) | RGS4RGS8P2RX3CYP1A2CYP3A4 | |
| SCHEMBL24327426 | 0.83 | P2RX3 (0.44) | RGS4RGS8P2RX3CYP2C19TLR7 | |
| SCHEMBL24327506 | 0.83 | CHRM5 (0.53) | RGS4RGS8P2RX3CHRM5CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |