Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | RGS4 | P49798 | 2/20 | 0.41 |
| ▸ | RGS8 | P57771 | 2/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328815 | 0.91 | RGS4 (0.50) | RGS4RGS8ALDH1A1TLR7MAPT | |
| SCHEMBL24327425 | 0.90 | P2RX3 (0.47) | P2RX3RGS4RGS8HSP90B1TRAP1 | |
| SCHEMBL24327426 | 0.88 | P2RX3 (0.44) | P2RX3RGS4RGS8HSP90B1TRAP1 | |
| SCHEMBL24327510 | 0.88 | RGS4 (0.52) | P2RX3RGS4RGS8DAOCHRM5 | |
| SCHEMBL24327423 | 0.86 | RGS4 (0.45) | P2RX3RGS4RGS8HSP90B1TRAP1 | |
| SCHEMBL24327921 | 0.84 | TRPV1 (0.48) | P2RX3RGS4RGS8CHRM5TLR7 | |
| SCHEMBL24327511 | 0.83 | RGS4 (0.46) | P2RX3RGS4RGS8THRBHSP90AA1 | |
| SCHEMBL24327512 | 0.81 | KIF11 (0.42) | P2RX3HSP90B1TRAP1DAOKDM4E | |
| SCHEMBL24327923 | 0.81 | RGS4 (0.60) | RGS4RGS8DAOALDH1A1TLR7 | |
| SCHEMBL24327506 | 0.80 | CHRM5 (0.53) | P2RX3RGS4RGS8HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |