Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 3/20 | 0.50 |
| ▸ | RGS8 | P57771 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328735 | 0.91 | P2RX3 (0.44) | RGS4RGS8TLR7ALDH1A1MAPT | |
| SCHEMBL24327923 | 0.90 | RGS4 (0.60) | RGS4RGS8CTSKTLR7TSHR | |
| SCHEMBL24327921 | 0.88 | TRPV1 (0.48) | RGS4RGS8CTSKTLR7TSHR | |
| SCHEMBL24327423 | 0.85 | RGS4 (0.45) | RGS4RGS8CTSKTLR7CYP3A4 | |
| SCHEMBL24327916 | 0.82 | RGS4 (0.44) | RGS4RGS8HPGDALDH1A1CYP3A4 | |
| SCHEMBL24327510 | 0.82 | RGS4 (0.52) | RGS4RGS8CTSKTSHRALDH1A1 | |
| SCHEMBL24327924 | 0.81 | PGR (0.49) | RGS4RGS8HPGDALDH1A1CYP3A4 | |
| SCHEMBL24327425 | 0.81 | P2RX3 (0.47) | RGS4RGS8TLR7ALDH1A1 | |
| SCHEMBL24327520 | 0.80 | C5AR1 (0.48) | RGS4RGS8TLR7TSHRHPGD | |
| SCHEMBL24327915 | 0.78 | NOX4 (0.53) | RGS4RGS8ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |