Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 6/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327490 | 0.91 | PGR (0.53) | ALDH1A1TSHRPGRPKMMEN1 | |
| SCHEMBL24327488 | 0.88 | DHODH (0.54) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL24327533 | 0.75 | MAPT (0.44) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11220891 | 0.74 | MAPT (0.59) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7178676 | 0.73 | PGR (0.71) | ALDH1A1TSHRPGRPKMCYP19A1 | |
| SCHEMBL3791521 | 0.72 | PGR (0.81) | ALDH1A1TSHRPGRPKMCYP1A2 | |
| SCHEMBL24327526 | 0.72 | DHODH (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL8251165 | 0.70 | PFKFB3 (0.67) | ALDH1A1TSHRPGRMEN1KMT2A | |
| SCHEMBL3756876 | 0.69 | PGR (1.00) | ALDH1A1PGRPKMMEN1KMT2A | |
| SCHEMBL14434547 | 0.69 | MAPT (0.65) | ALDH1A1TSHRPGRPKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |