Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | STK10 | O94804 | 1/20 | 0.49 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417404 | 0.86 | ADORA2A (0.58) | DHODHSTK10SLKADORA2AMPO | |
| SCHEMBL24327528 | 0.83 | AKT1 (0.52) | P2RX1P2RX4P2RX7TMPRSS4KIF11 | |
| SCHEMBL24327488 | 0.82 | DHODH (0.54) | DHODHSTK10SLKP2RX1P2RX4 | |
| SCHEMBL24327533 | 0.80 | MAPT (0.44) | DHODHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11220891 | 0.78 | MAPT (0.59) | DHODHSTK10SLKMEN1KMT2A | |
| SCHEMBL24327490 | 0.73 | PGR (0.53) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13961430 | 0.73 | ADORA2A (0.45) | DHODHSTK10SLKADORA2AMPO | |
| SCHEMBL12283415 | 0.72 | MAPT (0.61) | DHODHSTK10SLKMEN1KMT2A | |
| SCHEMBL24327496 | 0.72 | ALDH1A1 (0.56) | DHODHMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL24327534 | 0.71 | FFAR1 (0.41) | P2RX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |