Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327496 | 0.91 | ALDH1A1 (0.56) | PGRALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11220891 | 0.81 | MAPT (0.59) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL24327488 | 0.79 | DHODH (0.54) | ALDH1A1TSHRGAAMEN1KMT2A | |
| SCHEMBL24327533 | 0.77 | MAPT (0.44) | POLBALDH1A1GAAGFERMEN1 | |
| SCHEMBL24327526 | 0.73 | DHODH (0.54) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL24327929 | 0.73 | MAPT (0.51) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL8081768 | 0.72 | KEAP1 (0.79) | PGRPOLBALDH1A1IL1RNKEAP1 | |
| SCHEMBL3756876 | 0.71 | PGR (1.00) | PGRPOLBALDH1A1IL1RNKEAP1 | |
| SCHEMBL16719342 | 0.71 | IL1RN (0.66) | PGRPOLBALDH1A1IL1RNKEAP1 | |
| SCHEMBL12283415 | 0.70 | MAPT (0.61) | POLBALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |