Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 16/20 | 0.36 |
| ▸ | JAK3 | P52333 | 16/20 | 0.36 |
| ▸ | TYK2 | P29597 | 15/20 | 0.36 |
| ▸ | JAK2 | O60674 | 13/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327345 | 0.83 | JAK1 (0.40) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL29498911 | 0.83 | JAK2 (0.32) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327399 | 0.78 | AHR (0.41) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327878 | 0.77 | EPHB4 (0.42) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24328717 | 0.77 | JAK1 (0.37) | JAK1JAK3TYK2JAK2MAP3K5 | |
| SCHEMBL24327786 | 0.74 | JAK1 (0.39) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327409 | 0.72 | JAK1 (0.41) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327881 | 0.72 | JAK1 (0.37) | JAK1JAK3TYK2JAK2MAP3K5 | |
| SCHEMBL24327390 | 0.71 | JAK2 (0.43) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327989 | 0.69 | FGFR1 (0.39) | JAK1JAK3TYK2JAK2MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |