Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 20/20 | 0.39 |
| ▸ | JAK3 | P52333 | 20/20 | 0.39 |
| ▸ | TYK2 | P29597 | 19/20 | 0.39 |
| ▸ | JAK2 | O60674 | 18/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327345 | 0.82 | JAK1 (0.40) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327326 | 0.78 | JAK2 (0.43) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327405 | 0.78 | JAK2 (0.42) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327882 | 0.74 | JAK1 (0.36) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327409 | 0.72 | JAK1 (0.41) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24328717 | 0.71 | JAK1 (0.37) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL29498931 | 0.70 | JAK1 (0.34) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327390 | 0.70 | JAK2 (0.43) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327989 | 0.68 | FGFR1 (0.39) | JAK1JAK3TYK2JAK2 | |
| SCHEMBL24327856 | 0.68 | EGFR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |