Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | SPR | P35270 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 10/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328255 | 0.90 | GPR84 (0.54) | TSHRHTR2AHTR2CGPR84HTR1A | |
| SCHEMBL24328908 | 0.85 | MTNR1A (0.52) | TSHRHTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL24328904 | 0.84 | HTR2A (0.59) | TSHRHTR2AHTR2CGPR84MTNR1A | |
| SCHEMBL24328898 | 0.84 | KDM4E (0.67) | TSHRHTR2AHTR2CGPR84MPO | |
| SCHEMBL2615233 | 0.84 | HTR2A (0.66) | TSHRHTR2AHTR2CGPR84MPO | |
| SCHEMBL5790290 | 0.84 | HTR2A (0.66) | TSHRHTR2AHTR2CGPR84MPO | |
| SCHEMBL24328920 | 0.82 | TSHR (0.65) | TSHRHTR2AHTR2CGPR84MPO | |
| SCHEMBL24328903 | 0.82 | KDM4E (0.47) | TSHRHTR2AHTR2CMPOSLC6A4 | |
| Fluorotryptophane SCHEMBL122142 | 0.81 | HTR2A (0.73) | TSHRHTR2AHTR2CGPR84MPO | |
| Fluorotryptophane SCHEMBL125000 | 0.81 | HTR2A (0.73) | TSHRHTR2AHTR2CGPR84MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | TSHR 3476/4885HTR2A 3583/4885HTR2C 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.