Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328924 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2NR3C1NR3C2CDK2KDM4E | |
| SCHEMBL28393982 | 0.86 | KMT2A (0.61) | SMN1; SMN2NR3C1NR3C2PGRCDK2 | |
| SCHEMBL28393983 | 0.86 | KMT2A (0.61) | SMN1; SMN2NR3C1NR3C2PGRCDK2 | |
| SCHEMBL24328264 | 0.84 | NR3C1 (0.48) | SMN1; SMN2NR3C1NR3C2PGRCDK2 | |
| SCHEMBL24328923 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2NR3C1NR3C2PTPRAKDM4E | |
| SCHEMBL28414749 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2NR3C1NR3C2PTPRAKDM4E | |
| SCHEMBL6238687 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2NR3C1NR3C2PGRCDK2 | |
| SCHEMBL24328361 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2PTPRAKDM4EMAPTKMT2A | |
| SCHEMBL24328925 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2NR3C1PTPRAKDM4EMAPT | |
| SCHEMBL10078603 | 0.78 | CDK2 (0.53) | SMN1; SMN2NR3C1NR3C2PGRCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | SMN1; SMN2 3812/4885NR3C1 4561/4885NR3C2 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.