SCHEMBL24328381

SCHEMBL24328381

O=C(O)[C@H](Cc1ccc(O)cc1)OC1CC1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.49
SRR Q9GZT4 3/20 0.47
PPARA Q07869 14/20 0.46
PPARG P37231 15/20 0.45
PSAT1 Q9Y617 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24328378 0.88 SRR (0.61) SRRPPARAPPARG
SCHEMBL24328380 0.86 PPARG (0.57) SRRPPARAPPARG
SCHEMBL7299495 0.82 SRR (0.57) SRRPPARAPPARG
SCHEMBL7299501 0.82 SRR (0.57) SRRPPARAPPARG
SCHEMBL3996006 0.79 TYR (0.44) SLC7A5
SCHEMBL13793150 0.79 TYR (0.44) SLC7A5
SCHEMBL6590735 0.78 PPARG (0.66) PPARAPPARG
Hydrochloric Acid SCHEMBL7302958 0.77 SRR (0.54) SRRPPARAPPARGPSAT1
SCHEMBL5543269 0.77 PPARA (0.72) PPARAPPARG
SCHEMBL543815 0.77 PPARA (0.72) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS SLC7A5 22/4885SRR 3147/4885PPARA 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.