Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 7/20 | 0.40 |
| ▸ | IRAK1 | P51617 | 5/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327329 | 0.87 | EPHB4 (0.42) | IRAK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL24327879 | 0.82 | TEK (0.45) | JAK2JAK1TYK2JAK3EPHB4 | |
| SCHEMBL24327878 | 0.78 | EPHB4 (0.42) | TRPV3JAK2JAK1TYK2JAK3 | |
| SCHEMBL24327327 | 0.77 | TEK (0.47) | JAK2JAK1TYK2JAK3EPHB4 | |
| SCHEMBL24328759 | 0.70 | TEK (0.41) | TRPV3JAK2JAK1TYK2JAK3 | |
| SCHEMBL24328751 | 0.69 | IRAK1 (0.43) | IRAK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL24328734 | 0.69 | IRAK1 (0.43) | IRAK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL24328760 | 0.69 | IRAK1 (0.43) | IRAK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL24328753 | 0.68 | IRAK1 (0.42) | IRAK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL29498925 | 0.68 | MERTK (0.34) | JAK2JAK1TYK2JAK3EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |