Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 2/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327329 | 0.87 | EPHB4 (0.42) | TEKEPHB4NPBWR1SCDTYK2 | |
| SCHEMBL24327327 | 0.86 | TEK (0.47) | TEKEPHB4NPBWR1SCDADORA2A | |
| SCHEMBL24327878 | 0.85 | EPHB4 (0.42) | TEKEPHB4NPBWR1SCDTYK2 | |
| SCHEMBL24328762 | 0.82 | TRPV3 (0.40) | TEKEPHB4SCDTYK2KCNH2 | |
| SCHEMBL24328759 | 0.76 | TEK (0.41) | TEKEPHB4NPBWR1SCDKDR | |
| SCHEMBL24328751 | 0.75 | IRAK1 (0.43) | TEKEPHB4KDRTYK2CHEK1 | |
| SCHEMBL24328760 | 0.75 | IRAK1 (0.43) | TEKEPHB4KDRTYK2CHEK1 | |
| SCHEMBL24328734 | 0.75 | IRAK1 (0.43) | TEKEPHB4KDRTYK2CHEK1 | |
| SCHEMBL24327773 | 0.71 | KCNH2 (0.55) | TEKEPHB4NPBWR1KCNH2MAPK1 | |
| SCHEMBL24328691 | 0.71 | EPHB4 (0.46) | TEKEPHB4NPBWR1TYK2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |