Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27084998 | 0.98 | HTR2A (0.59) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL27084806 | 0.94 | HTR2A (0.54) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL25425515 | 0.91 | HTR2A (0.55) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL24168355 | 0.91 | HTR2A (0.55) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL24168730 | 0.90 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL30630389 | 0.90 | HTR2A (0.68) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| Hydrochloric Acid SCHEMBL30498783 | 0.90 | HTR2A (0.55) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| Methyl Alcohol SCHEMBL25423744 | 0.90 | HTR2A (0.55) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL27085247 | 0.89 | HTR2A (0.52) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL24168863 | 0.89 | HTR2A (0.56) | HTR2AHTR2CHTR2BHTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | COMPASS PATHFINDER LIMITED (GB) | 2024-02-08 | — | — | US | disclosed |
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20220177427-A1 | Tryptamine Prodrugs | REUNION NEUROSCIENCE CANADA INC. (CA) | 2022-06-09 | — | — | US | disclosed |
| US-11292765-B2 | Tryptamine prodrugs | FIELD TRIP PSYCHEDELICS INC. (CA) | 2022-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292765-B2 | Tryptamine prodrugs | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR2C 3/4885HTR2B 8/4885 |
| US-20240043382-A1 | MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES | INMT, AANAT, HNMT | HTR2A 53/4885HTR2C 482/4885HTR2B 514/4885 |
| US-20220177427-A1 | Tryptamine Prodrugs | HTR2A, HTR5A, HTR2C | HTR2A 1/4885HTR2C 3/4885HTR2B 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.